4. Enlarged lymph nodes and organs
As noted before, aberrant lymphocytes not only stay in the blood marrow and the blood. They migrate to other organs and deposit in lymph nodes, the spleen, and the liver. As they do so, lymph nodes become swollen, and your doctor may also detect an increase in the size of your liver and spleen. This is detected either by physical examination or imaging studies when it is a mild enlargement.