Acute Myeloid Leukemia Prognosis and Survival Rate

What are the odds of survival?

Several factors come into play when estimating a survival period for acute leukemia. Overall, about 20-25 % of people diagnosed with AML survive for more than 5 years. This, however, varies widely depending on age. For instance, patients younger than 20 years old at diagnosis have a 70% 5-year survival rate, but since acute myeloid leukemia affects older people with a higher prevalence, the overall ratio tends to be lower.

Another critical factor is the therapy introduced to the patient. In young patients, the option for stem cell transplantation is viable and can increase survival rate dramatically when done in the first 5 years of the disease. On the other hand, it is usually avoided in patients older than 60 years old since they are likely to develop tissue rejection, which can be fatal. High doses of chemotherapy introduced to younger individuals also increase the chances of a complete remission, while they may be contraindicated in older individuals in whom it can cause a lethal toxic effect.