Bone marrow biopsy pain
Pain is a defense mechanism that we developed to protect and alert us against dangers to our bodies. If we understand this, we will realize that in fact, many of our internal organs have no pain receptors. Our brain itself has no pain receptors, but the skin is full of them. In the bone, pain receptors are mainly found on the covering of the bones -scientifically called the periosteum-. So, when the doctor sticks a needle into your bone marrow, it is normal to be extremely painful. The pain is triggered by the bone receptors on the skin, muscles, tendons and periosteum.
However, you will not feel excruciating pain because all bone marrow procedures are done under anesthesia. Pain itself is influenced by many factors such as age, obesity, anxiety and the length of the procedure.