Treatment of T-ALL
In the pediatric and adult population, T-Cell Acute lymphoblastic leukemia usually involves a higher risk than B-Cell Acute lymphoblastic leukemia. There’s a higher risk, which is translated into a higher chance of resistance to treatment, a higher tendency for relapse, and a higher chance of involvement of the central nervous system.
For this reason, it is important to treat T-ALL aggressively from the start, and treatment protocols usually include a combination of chemotherapeutic treatments and radiation therapy. According to research, the intensification of this multimodal treatment has led to significant improvement in the management of the disease. Treatment should start immediately, and any delay may further compromise the patient and lead to a poor prognosis.
Treatment modalities typically include:
– Radiotherapy
It is sometimes used, especially in cases of involvement of the central nervous system.