Top 15 Common Questions About Leukemia

What is the most common cause of low platelet count?

Among common causes of low platelet count, we can have a reduction in their production by the bone marrow, but also viral infections that reduce this number, including the Epstein Barr virus, rubella, and many others. Platelets may also be destroyed in the bloodstream by autoimmune conditions such as systemic lupus erythematosus, HIV infections, medication-induced low platelet counts, and as an immediate result of blood transfusion. In cases of malignant hypertension and Hellp syndrome, the low platelet count is also a possibility. They may even become sequestered and eliminated by the liver or the spleen. Thus, there are many different causes we should rule out if you have a low platelet count, and many.

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