Splenectomy (Spleen Removal); Splenectomy Indications & How Is Splenectomy Done?

2. Thalassemia

Thalassemia
Thalassemia

Thalassemia is a blood disorder that involves an abnormal hemoglobin production which causes the red cells to have a short life span. The spleen enlarges because of this rapid destruction and because of the anemia that causes what is called extramedullary hematopoiesis, which is the production of red cells in sites outside the bone marrow to compensate for the rapid destruction, and those sites include the spleen.