Autologous and Allogeneic Transplant | Stem Cell Transplant

Umbilical cord blood and peripheral blood

Umbilical cord blood

Although the terms stem cell transplantation and bone marrow transplantation have been used interchangeably in this article, not all stem cell transplantation techniques use bone marrow cells. Stem cells are also found in the normal peripheral blood and the umbilical cord, and modern techniques have allowed for their collection with increasing accuracy. The first umbilical cord blood collection was actually done in the 80s.

This procedure involves the collection of umbilical cord blood from the fetal umbilical cord after clamping it at birth and then preserving it in blood banks whether national or private for future use. This can also be done as an allogeneic stem cell transplant with an increased success rate and decreased risk for graft-versus-host disease than bone marrow samples because umbilical cord cells are less mature and less differentiated to develop an immune reaction against the host.